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KMID : 0387720160270020105
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Korean Journal of Blood Transfusion
2016 Volume.27 No. 2 p.105 ~ p.112
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The Change in Distribution of Red Blood Cell Antigens in Korean Youth: In an Era of Multicultural Society
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Shin Kyung-Hwa
Kim Hyung-Hoi
Lee Hyun-Ji
Ahn Tae-Young
Park Kyoung-Un
Hong Yun-Ji
Kwon Jeong-Ran
Choi Young-Sill
Kim Jun-Nyun
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Abstract
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Background: It is important to check the blood group antigens to ensure the safety of blood transfusions. Recently, the number of multicultural families and foreigners has increased in Korea; therefore, a survey for red blood cell antigens for multicultural families is need. We performed a phenotyping of their red blood cell antigens and found the characteristics in providing basic data.
Methods: We recruited young people under the age of 26 years from multicultural family between September 2015 and March 2016. The participants were divided into two groups: the multicultural youth group (MCY) and the non-multicultural youth group (non-MCY). Subjects underwent phenotyping of ABO, Rh, Kell, Kidd, Duffy, MNS, and Diego blood group, and the results were compared and characterized between the two groups.
Results: A total of 226 subjects (89 MCY, 137 non-MCY) were recruited. The blood groups with differences between MCY and non-MCY were E, e in Rh and S in MNS. In MCY, the frequency of CDe expression in the Rh blood group was higher and the cDE expression was lower. There were 3.4% and 2.2% of MCY with no expression of Fya and s, respectively, which were rare blood types in Koreans.
Conclusion: The difference in frequency of red blood cell antigens between MCY and non-MCY have been identified. These results suggest that the national blood policy reflects an increasing number of multicultural families and Korea needs to be prepared for a population change.
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KEYWORD
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Blood group antigens, Rh-Hr blood Group system, Korea
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